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Departments:
Biology
Cell Biology
Mathematics
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Earth & Ocean Sciences
Biomedical Engineering
Civil & Environmental Engineering.
Electrical and Computer Engineering.
Mechanical Engineering & Materials.Science
Neurobiology
Nicholas School of.the.Environment
Psychiatry and Behavioral Science
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A Sampling of CNCS Research
Projects
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Stress
Patterns in Granular Materials
Dr. Behringer, Graduate student Bob Hartley
This experiment looks at the role of friction in granular silos when
the bottom floor is raised quasi-statically (very slowly). When disks
made of a special plastic are placed between appriopriately designed polarizers
and backlit, the ones experiencing higher stresses light up. The
disks are approximately 5mm in diameter. The photo shows the stress
in the system at the start and after slowly pushing the bottom with a piston
through approximately 1.5 cm. Analysis of the pattern of stress chains
will clarify the mechanisms by which dry granular materials such as sand,
coal, rice, or pills respond to external loads.
This experiment is being carried out in collaboration with researchers
Evelyne Kolb and Guillaume Overlez from the University Pierre & Marie
Curie in Paris. |
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Spatial
Structure and Evolutionary Stability
Drs. Socolar and Wilson, Postdoc Shane Richards
To understand
the population dynamics of biological systems it is sometimes necessary
to take into account the spatial structure of the population. That
is, different types of organisms subject to the same external environmental
pressures may thrive or not, depending on how the individuals tend to be
arranged in space. For example, a species that tends to form dense
clusters may be more susceptible to extinction due to a disease that has
only a minor effect on a species that tends to be more sparsely distributed.
The figure at right shows a snapshot of a simulation of simple "organisms"
that remain stationary and are characterized by a single trait: their natural
mortality rate. Individuals with the average mortality are gray,
those with smaller (or larger) are green (or red). Individuals are
born next to their parent, inheriting their parent's mortality rate plus
a small random mutation. They die either from natural causes or from
diseases, which are very rare. The disease kills all organisms that
belong to the connected cluster where it originates. The total spread
in mortality rates represented in this picture is about 10% of the average.
he emergent spatial structure in the model we have investigated is of
interest both for bioligists and physicists. First, it is a crucial
ingredient in the evolutionary stability of this simple system. The
mechanism that selects for a stable natural mortality rate is based entirely
on the different spatial properties of colonies with different mortality
rates, not on the traits of individual organisms. Second, it is an
example of a nonequilibrium physical structure that arises as a solution
to a complex optimization problem, and may be characterized as a "self-organized
critical" structure leading to a power-law distribution of epidemic sizes. |
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Nonlinear Dynamics of Complex Fluid/Structure Interaction
Drs. Dowell, Virgin, Howle
This
central theme covers a variety of specific projects that are supported
by the Air Force Office of Scientific Research, DARPA, the Office of
Naval Research, and NASA. The physical phenomena are concerned with
the linear and nonlinear dynamic instabilities and limit cycle
oscillations that may arise from the interaction between a flexible
structure and a surrounding convecting fluid flow. Aircraft, naval
craft and rotorcraft and their propulsion systems are important
examples where such issues arise in practice, although comparable
phenomena arise in bioengineering (blood flow through arteries),
biological marine propulsion, civil engineering (osillations of long
span bridges and tall buildings in high winds) and other fields of
science and technology. The major research issues are how to deal with
the complexity of very high dimensional systems on the order of a
million degrees of freedom that describe the fluid/ structure system
and how to identify and model the wide range of nonlinear effects that
may be important. The latter include structural freeplay,
geometrically large motions and non-classical damping as well as fluid
shock waves and turbulence. Of course, several of our studies focus
solely on a fluid or structural system.
The theoretical and experimental methods run the full gamut of modern
techiques developed by the nonlinear dynamics research community
including basin boundary construction, dimensional determination, and
characterization of chaos. New developments receiving special
emphasis are control of nonlinear oscillations, determination of
stability of limit cycle oscillations based upon experimental data,
system identification and determination of isola through continuation
methods and the development of Proper Orthogonal Decomposition
techniques to extract the dominant eigenmodal features of very high
dimensional systems.
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Characterizing and Controlling Cardiac Dynamics
Drs. Gauthier, Krassowska, Wolf, Schaeffer, Socolar
One
intriguing application of the chaos control methods we have developed
is in the biological area. We have initiated a program to
characterize in vitro the dynamics of small pieces of rapidly paced cardiac
muscle and to use feedback methods to suppress or
control the observed bifurcations by applying small perturbations to the
tissue. We find that there are only a small number of classes
of bifurcations in the tissue, but that there is significant variation in
the prevalence of these behaviors from animal to animal.
In addition, we are using similar methods to control in vivo a fibrillating
sheep atrium. The eventual long term goal of this project is to
develop an implantable defibrillator that will maintain a healthy rhythm in
humans prone to the onset of atrial fibrillation using only
small electrical shocks. In our current experiments with sheep, we use a
high-density mapping system to record the spatial-temporal
complexity occurring on the surface of the heart during atrial
fibrillation. Small control shocks are applied to a single electrode
attached to the surface of the heart based on real-time measurements of the
cardiac dynamics at a nearby spatial location.
This research is collaboration with Mr. Robert Oliver and Ms. Soma Sau
(graduate students in Biomedical Engineering), and Profs. Wanda Krassowska
(Biomedical Engineering), David Schaeffer (Mathematics), Joshua Socolar
(Physics), and Patrick Wolf (Biomedical Engineering).
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Coating Flows and Contact Line Dynamics
Drs. Bertozzi, Witelski, and Behringer; Postdoc Mark Bowen
Coating flows and moving contact lines arise in a diverse range of
applications including the design of paints, the liquid lining of the
lungs, and microchip coatings. Driven films often undergo `fingering'
instabilities seeded by surface imperfections. Recent studies show
that by driving the film with a surface stress while maintaining an
opposing body force, new dynamics, involving stable undercompressive
fronts, are possible. At right, the output of a numerical simulation
of the dynamics shows the beginning of the interaction of the front
with some imperfections in the surface.
This work is being done in collaboration with Dr. Michael Shearer of NCSU.
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